Charles Rogers, Michigan State
The Detroit Lions made Michigan State wide receiver, Charles Rogers, the second overall pick in the 2003 NFL Draft. At the time, few people disagreed with the pick. In his two seasons with the Spartans, Rogers broke numerous receiving records and finished with 2,821 yards and 27 touchdowns. Rogers was thought to be the best player in college football — regardless of position.
But issues with injuries and a subsequent addiction to painkillers resulted in his demise. In three NFL seasons, Rogers totaled just 36 receptions and was out of the league by 2005.