2010: C.J. Spiller, RB, Buffalo Bills
With #9 pick in the first round, the Buffalo Bills selected Clemson running back C.J. Spiller. In college, Spiller was a human highlight reel, and a human Swiss-Army knife on the football field. He did it all, and he did it well. In his senior year, Spiller rushed for over 1,200 yards, had more than 500 yards receiving, and scored 5 touchdowns on kickoff and punt returns. But up against better competition, Spiller never found that magic in the NFL.
His lack of size (5-foot-11 and 200 pounds) limited him to 38 starts, throughout his injury plagued career. In the past three seasons Spiller has played for four different teams, and has been cut and resigned by the Chiefs three times in 2017.
By taking Spiller at the top of the draft, Buffalo passed on a boatload of talented players; safety Earl Thomas, defensive end Jason Pierre-Paul, tight end Rob Gronkowski, and receivers Demaryius Thomas and Dez Bryant.