2001. Drew Brees (Pick: Michael Vick)
Want to talk about hitting a grand slam with your first two draft picks? After the San Diego Chargers traded down from the #1 overall pick in the 2001 NFL Draft (passing on the chance to select quarterback Michael Vick), the Chargers took Hall of Fame running back LaDainian Tomlinson with their first round pick, and future Hall of Fame quarterback Drew Brees with their second round pick.
Brees holds the NFL records for career pass completions, career completion percentage, career passing yards, is second in career touchdown passes, third in regular season career passer rating, and fourth in postseason career passer rating.