Curtis Enis – Penn State
An All-American in high school and at Penn State, running back Curtis Enis was a highly coveted player entering the 1998 NFL Draft. It’s rumored that the Jacksonville Jaguars offered two first round picks to move up in the draft to select Enis. Thankfully for the Jags, the Bears didn’t take that generous deal, and the Jags ended up taking Fred Taylor instead.
Enis, the 5th-overall pick, suffered a knee injury during his rookie season, and was never the same player. Injuries continued to plague him throughout his career, and Enis eventually developed a degenerative knee condition when he was just 24 years old.
He retired in 2001, having rushed for a grand total of 1,497 yards and four touchdowns in his NFL career… Not exactly the type of production you’re hoping for from a top 5 pick.