While Eddy Curry definitely deserves to be on this list — he reportedly weighed over 350 pounds before he turned 30 years old — his situation might be unique. The Chicago Bulls, who drafted Curry in 2002, believed that Curry might have been predisposed to a heart condition known as hypertrophic cardiomyopathy. It is entirely possible that this condition severely limited his conditioning and overall ability to stay in shape. His stats and overall ability continued to decrease as his weight became more and more of an issue for the rotating cast of coaches he played for. Coach Scott Skiles once said that Curry needed to actually “jump” if he wanted to be a better rebounder, and Mike D’Antoni openly said that Curry would need to lose weight if he wanted to play for him. In 2009, even after losing 30 pounds, a Knicks trainer said it was “delusional” to think Curry would ever return to his listed playing weight of 285 pounds.